A further unanticipated outcome was that super-lean individuals had much higher than expected metabolic rates when they were resting, which they found was linked to higher levels of circulating thyroid hormones.
An additional surprise was that in super-lean people, their cholesterol and triglyceride profiles were indicative of good cardiovascular health. Scientists did not expect this given how inactive they were suggesting, they say that their low activity was potentially offset by their lean body composition.
This study is unique in that, as opposed to the traditional dietary survey methods, the team used an isotope method to accurately measure energy expenditure and from that could infer their food intake. This is considered to be a much more accurate approach as it does not rely on self-reported intake, which is subject to error. They also used accelerometers to objectively measure how much they actually moved, rather than relying on self-reported activity.
The team gathered data from more than 150 adults who met the low BMI criteria, and 150 people with normal BMI. The volunteers were screened to exclude individuals with eating disorders or other illness which may have affected their diet or mobility.
“The results came as a real surprise,” said Professor John Speakman who led the research.
“Often when people talk to super-lean individuals, they say that they can eat whatever they want. But our work showed that what they actually eat is much less than people in the normal BMI range.
“Of course, there still could in theory be people with the eat whatever they want and burn it all off by high levels of exercise, it’s just none of the 150 people who volunteered to join our study showed that pattern.”
Co-first author Sumei Hu said “It was a big shock to me that the super-lean individuals were much less active than people in the normal BMI range.
“I always thought super-lean individuals must be really active to keep their low body weight, but our results showed the opposite – we found that super-lean individuals were about 23 per cent less active than those of normal weight.”